He was a member of the New Garden Quaker Community in Pa. as early as 1719. In 1724 he move he. to the west in Pequea Creek district ( present day Lancaster Pa. ). In 1730 he and Alexander Ross, another Quaker from New Garden, purchased 100 thousand acres of land on the waters of Qpeqoun Creek ( near the present town of Winchester Va. ). In 1734 Morgan Bryan purchaes a tract in present day Berkeley Co. WV and there he settled with his famiy. In 1748 Bryan moved himself and his large family to North Carolina where he made his home near the south bank of Deep Creek and wasone of the most prominet settlers of northwest North Carolina.